Instead of throwing everything in one list, you get a separate column for each priority. The “Current” column has really important stuff.
Each task gets a difficulty rating on 1 to 5 scale. Why? So you can recognize the quick wins and get them out of the way.
If a task is not actionable at the moment, just hit the snooze button and it will come back when it's time to get back to it.
Use ⌘K to jump to lists and tasks. Navigate using Vim bindings. Keyboard shortcuts for everything. Have we mentioned it works offline?